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By P. Serra

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22 Biosensors for Health, Environment and Biosecurity pH=7(10-20%). The data in shows the sensor is sensitive to the concentration of the polar liquid and therefore could be used to differentiate between liquids into which a small amount of leakage of another substance has occurred. The conductance of the rods was higher under UV illumination but the percentage change in conductance is similar with and without illumination. 1 pH over the entire pH range, showing the remarkable sensitivity to relatively small changes in concentration of the liquid.

AlGaN/GaN High Electron Mobility Transistor Based Sensors for Bio-Application 39 Fig. 19. Schematic of HEMT sensor functionalized for PSA detection. Fig. 20. 2 Kidney injury molecule detection Problems such as Acute Kidney Injury (AKI) or Acute Renal Failure (ARF) are unfortunately still associated with a high mortality rate (Thadhani, Pascual and Bonventre 1996, Chertow et al. 1998, Bonventre and Weinberg 2003). An important biomarker for early detection of AKI is the urinary antigen known as kidney injury molecule-1 or KIM-1(Ichimura et al.

25 μg/ml to 17 μg/ml. 4 Lactic acid detection Lactic acid can also be detected with ZnO nanorod-gated AlGaN/GaN HEMTs. Interest in developing improved methods for detecting lactate acid has been increasing due to its importance in areas such as clinical diagnostics, sports medicine, and food analysis. An accurate measurement of the concentration of lactate acid in blood is critical to patients that are in intensive care or undergoing surgical operations as abnormal concentrations may lead to shock, metabolic disorder, respiratory insufficiency, and heart failure.

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