By George Britton, Synnove Liaaen-Jensen, Hanspeter Pfander
The Carotenoids book sequence presents particular debts of the basic chemistry of carotenoids and the elemental tools utilized in carotenoid study, and significant discussions of the biochemistry, services and functions of those very important compounds.
The ultimate quantity, Volume 5, bargains with the subject that's of maximum basic curiosity and public situation, carotenoids in human healthiness and foodstuff. this is often the period of ‘functional foods’, and choosing roles of chemical parts of meals as very important micronutrients. Carotenoids function excessive at the checklist of those. Volume 5 follows the carotenoid tale from meals to organic activities.
Carotenoids, quantity 5 is deliberate as a coordinated, built-in remedy offering updated and demanding study surveys by way of best specialists within the box, and incorporating a few heritage fabric to assist make the chapters obtainable to carotenoid researchers who're now not experts at the specific topic.
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Extra info for Carotenoids: Nutrition and Health
Three chapters describe experimental approaches and strategies for the study of other health effects of carotenoids. There have been extensive epidemiological surveys to identify associations between carotenoids, either from normal dietary intake or administered in intervention trials, and relative risk of serious conditions such as cancer and coronary heart disease. Chapter 10 describes the various experimental designs, how data are obtained and evaluated, and the strengths and limitations of the various Editors’ Introduction: A Healthy Debate 5 methods.
Carotenoids in Health and Disease, CRC Press, Boca Raton, USA (2004). IARC/WHO, Handbook of Cancer Prevention, Volume 2: Carotenoids, International Agency for Research on Cancer, Lyon, France, (1999). Carotenoids Volume 5: Nutrition and Health © 2009 Birkhäuser Verlag Basel Chapter 2 Analysis of Carotenoids in Nutritional Studies Frederick Khachik A. Introduction The ability to establish a statistically sound relationship between dietary intake of carotenoids and the incidence of chronic disease requires detailed knowledge of the qualitative and quantitative distribution of these compounds in the food supply as well as in human blood, major organs, and tissues.
Separation of carotenes Reversed-phase HPLC is normally used for the separation of the hydrocarbon carotenes. Most C18 columns will give some separation but the selectivity varies considerably with the different kinds of stationary phases. The main structural features that determine separation are: (i) Cyclic or acyclic end groups. g. lycopene (31) → γ-carotene (12) → β-carotene (3). γ-carotene (12) (ii) Double-bond position in cyclic end groups. For cyclic end groups the β ring has greater affinity for the stationary phase than does the ε ring, leading to the elution order ε-carotene (ε,ε-carotene, 20) → α-carotene (β,ε-carotene, 7) → β-carotene (β,β-carotene, 3).